What have our scientist have been up to?

 
 

Developing a predictive model for perinatal morbidity among small for gestational age infants

This study’s objective is to identify factors that are independently associated with morbidity among neonates with low birth weight.

Blue, N. R., Allshouse, A. A., Grobman, W. A., Day, R. C., Haas, D. M., Simhan, H. N., Parry, S., Saade, G. R., & Silver, R. M. (2021). Developing a predictive model for perinatal morbidity among small for gestational age infants. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 1–10.

 

Trajectories of antenatal depression and adverse pregnancy outcomes

This study asks how the trajectory of depressive symptoms during pregnancy is associated with different risks of adverse pregnancy outcomes. The researchers concluded that women with depressive symptoms that worsen as pregnancy progresses have increased odds of preterm birth.

Miller, E. S., Saade, G. R., Simhan, H. N., Monk, C., Haas, D. M., Silver, R. M., Mercer, B. M., Parry, S., Wing, D. A., Reddy, U. M., & Grobman, W. A. (2021). Trajectories of antenatal depression and adverse pregnancy outcomes. American journal of obstetrics and gynecology, S0002-9378(21)00793-6.

 
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Weight gain in early, mid, and late pregnancy and hypertensive disorders of pregnancy

In this observational study, researchers found that excessive weight gain as early as the early second trimester was associated with increased risks of development of HDP.

Dude, A. M., Kominiarek, M. A., Haas, D. M., Iams, J., Mercer, B. M., Parry, S., Reddy, U. M., Saade, G., Silver, R. M., Simhan, H., Wapner, R., Wing, D., & Grobman, W. (2020). Weight gain in early, mid, and late pregnancy and hypertensive disorders of pregnancy. Pregnancy hypertension, 20, 50–55.

 

One step versus two step approach for gestational diabetes screening: systematic review and meta-analysis of the randomized trials

The one and the two step approaches were not associated with a significant difference in the incidence of GDM. However, the one step approach was associated with better maternal and perinatal outcomes.

Saccone, G., Caissutti, C., Khalifeh, A., Meltzer, S., Scifres, C., Simhan, H. N., Kelekci, S., Sevket, O., & Berghella, V. (2019). One step versus two step approach for gestational diabetes screening: systematic review and meta-analysis of the randomized trials. The journal of maternal-fetal & neonatal medicine : the official journal of the European Association of Perinatal Medicine, the Federation of Asia and Oceania Perinatal Societies, the International Society of Perinatal Obstetricians, 32(9), 1547–1555.

 

Stress during pregnancy and gestational weight gain

The findings of this study whos that lower reported stress, as measured by the Life Experiences Survey, was associated with a greater chance of women achieving adequate gestational weight gain. This relationship highlights the potential for interventions directed toward psychosocial support to have salutary effects upon gestational weight gain.

Kominiarek, M. A., Grobman, W., Adam, E., Buss, C., Culhane, J., Entringer, S., Simhan, H., Wadhwa, P. D., Kim, K. Y., Keenan-Devlin, L., & Borders, A. (2018). Stress during pregnancy and gestational weight gain. Journal of perinatology : official journal of the California Perinatal Association, 38(5), 462–467.